Careers

Working Together Toward a Shared Vision

At Allena, we’re proud of our dynamic, thoughtful and engaging culture, and we are always looking for outstanding professionals to join our team.

We are innovators and collaborators. We fully appreciate our responsibility to the patients and to our stakeholder community, which is supporting our efforts to advance the development of novel oral enzyme therapeutics to treat complex metabolic complications.

To be considered for one of the positions below, please complete the form below and send us your resume. 

Clinical Scientist

Description

The clinical scientist is a key member of the clinical development team and is a major contributor to the development and execution of the clinical strategy for our development programs. The successful candidate will interface with the clinical development team to provide scientific and medical expertise to current and future clinical programs, and with medical affairs and business development (including investor relations) to provide data-driven scientific and strategic inputs.

Who are we looking for?

  • Energetic individual who will work with the Clinical Development team contributing to a variety of novel projects and is interested in a laboratory centric career 
  • Must have 3+ years of laboratory experience supporting drug development in a laboratory environment.
  • Leading the way:  A learning-agile and strategic scientist willing to challenge the status quo
  • Ownership:  A partner to jointly own our company’s goals, execution and success
  • Working together:  A colleague to thrive on collaboration with our teammates
  • Loving what you do:  A team member with positive energy that is passionate about our mission

What are we looking for?

  • A creative and focused (attention to details is a must) scientist, able to consistently deliver results to drive research projects forward
  • A colleague to join our lab as both an individual and team contributor
  • A team member with positive energy who is passionate about asking questions and finding answers.
  • Excellent communication and presentation skills both written and verbal.

What are we offering?

  • Membership within a growing, CARING and collegial organization
  • An opportunity to grow with the Clinical Development role 
  • Exposure to pioneering science of the therapies that utilize the GI tract to degrade metabolites

Responsibilities:

  • Contribute to the design and execution of assigned clinical study(ies) in close collaboration with lead study MD and Clinical Operations, and for earlier stage assets, with non-clinical experts, to include safety oversight, trial conduct in accordance with protocol, review of emerging data, etc. 
  • Contribute to and/or lead, as relevant, the preparation of documents including protocols and protocol amendments, preparation of statistical analysis plan(s), preparation of abstracts/posters/manuscripts, and presentations, collaborating with internal and external contributors; write original content as appropriate. 
  • Participate in the review, analysis, interpretation and presentation of accurate study results, including preparation of investigator brochure, annual safety reports, clinical study reports and other documents associated with regulatory submissions. 
  • Build deep knowledge of the therapeutic area(s) relevant to Allena, including current medical practice, existing Allena development programs and study results, competitive intelligence, etc, in order to effectively support Medical Affairs and Business Development with data and information requests.
  • Undertake literature searches and summaries; remain up to date with scientific advances; maintain or oversee maintenance of Allena electronic library. Support investor relations initiatives in providing competitive landscape summaries/briefings.
  • Provide support for Advisory Board meetings, Allena presence at national and/or regional scientific meetings, investigator meetings, etc, including preparation and/or delivery of presentations; working closely with relevant stakeholders. 
  • Cultivate and/or support relationships with external partners such as clinical investigators, clinicians, and scientists in support of trial execution and business development
  • Other responsibilities as they evolve over time. 

Education and Experience: 

  • PhD in the life sciences.  Master’s degree in the life sciences considered if extensive relevant work experience as a clinical scientist with demonstrated ability to work independently.
  • Experience (3+ years) working as a clinical scientist within a pharmaceutical/biotechnology company or other relevant role managing data and document preparation within the life sciences.

Skills/Abilities: 

  • Personal drive and confidence to act as SME to provide scientific and medical expertise to current and future clinical programs, and with medical affairs and business development to provide data-driven scientific and strategic inputs.
  • Innovative and collaborative style.
  • Proven success interfacing with clinical development teams. 
  • Ability to function in a chemical laboratory environment; should have no known sensitivities to chemicals present in the laboratory and no health conditions that preclude working in a chemical laboratory environment. 

Competencies:

Adaptability: Responds resourcefully, flexibly, and positively when faced with new challenges, transitions, and demands. Willingly and effectively deals with the stress and complexities of various situations. Moves forward productively and optimistically under conditions of change and uncertainty.

Collaboration: Embodies and promotes collaboration and works effectively with others across the organization to achieve goals. Demonstrates proficient cross-company communication, cultural sensitivity, and partnership in interactions with others.  Involves others in decisions and plans and credits them for their contributions and accomplishments.

Communication: Creates an environment which promotes the free flow of communication and information throughout the organization. Communicates effectively in large and small groups. Openly shares knowledge and expertise. Listens actively and encourages the open expression of ideas and opinions.

Execution: Drives execution of strategic and operating plans while maintaining operational effectiveness. Conveys a strong sense of urgency around continuous improvement, achieving high quality results, and accelerating business performance. Addresses problems directly and drives changes necessary to achieve business objectives.

Relationship Building: Establishes and maintains strong relationships internally and externally. Respects and relates well to management, colleagues, peers, and direct reports. Champions a culture of respect, diversity and inclusion that values and respects individuals. Earns the respect of others through principled leadership, sound business ethics, and authenticity.

Location: Newton & Sudbury, MA

NOTE: This role could be 100% remote for the right candidate.

TO ALL AGENCIES: Please, no phone calls or emails to any employee of Allena about our openings. All resumes submitted by search firms/employment agencies to any employee at Allena via email, the internet or in any form and/or method will be deemed the sole property of Allena, unless such search firms/employment agencies were engaged by Allena for this position and a valid agreement with Allena is in place. In the event a candidate who was submitted outside of the Allena agency engagement process is hired, no fee or payment of any kind will be paid.

Allena Pharmaceuticals, Inc. is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law.

Senior Director, Process Technology

Description:

The Sr. Director of Process Technology is a highly visible role. He/She will establish the strategy, project plans, and timelines for internal/external process development efforts to characterize and optimize the late-stage Reloxaliase process as a lead-in to process validation, commercialization and process monitoring. Additionally, the Director/Sr Director of Process Technology will grow the PD function within the company and lead the creation of subsequent manufacturing processes for clinical candidate compounds with an emphasis on translating academic/R&D processes into scalable, robust methods suitable for industry and subsequent technology transfer into a GMP manufacturing environment.

The individual chosen for this role will work in close partnership within a matrixed environment by regularly interfacing with diverse teams and functions including MSAT, Quality, Regulatory, Legal, Analytical Development, and Program Management.

Responsibilities:  

The Sr. Director of Process Technology will be responsible for primarily downstream PD activities with some peripheral involvement in upstream development activities. Those duties include:

  • Assessing and refining the strategy for Allena’s PD group with an immediate focus on completing the actual process development and “locking” the process to be used for GMP runs and PPQ (process validation) of our lead candidate
  • Working closely with other necessary department heads to develop a tech transfer plan for processes coming from PD and moving into GMP manufacturing
  • Lead an internal team consisting of Analytical Development, MSAT and External Manufacturing to determine a robust Process Performance Qualification (PPQ) protocol strategy, to include generation of appropriate acceptance criteria
  • Responsible for the all stages of process development for all programs within the pipeline
  • Oversee the development and implementation of an (upstream and downstream) process monitoring/control strategy program using appropriate statistical guidelines
  • Provide expert and scientific input into the development and implementation of drug substance and drug product release specifications 
  • Leads authoring efforts for specific CMC sections of regulatory filings (including INDs, BLA’s, and formal responses to regulatory inquiries)
  • Drives innovation from ideation to realization for process improvements, including definition of technology roadmap, justification of projects, and developing implementation plans.
  • Support business cases and CAPEX justifications for capacity expansion, facility build-outs and acquisitions
  • Participates in planning to ensure alignment between resource availability and project pipeline 

Skills/Abilities:

  • Leading the way:  A ‘hands-on’ and strategic PD professional willing to challenge the status quo and provide creative solutions to identified challenges
  • Ownership:  A partner to jointly own our company’s goals, execution and success
  • Working together:  A colleague to thrive on collaboration with our teammates
  • Loving what you do:  A team member with positive energy that is passionate about our mission
  • A demonstrated self-starter who is excited by the challenge of commercializing a late-stage product and values the direct impact he/she will have on the lives of our patients
  • Willing and able to work at whatever operational level needed to meet the goals of the function 
  • Highly motivated and ability to take a proactive approach on the job
  • Has a solid understanding of business and financial fundamentals

Education and Experience:

  • PhD, MS or a BA/BS and equivalent relevant experience: 8-12+ years of experience in large-molecule, biologics-related Process Development
  • Must have expertise in and be able to demonstrate a deep understanding of end-to-end bioprocessing strategies to include the current state of the art analytical tools used to evaluate them
  • Has a deep technical understanding of large-molecule and large-scale manufacturing platforms
  • Demonstrated experience in late-stage product development including execution of product risk assessments, implementation of Quality by Design and integration of RA and QbD into process validation protocols and BLA submissions
  • An excellent leader with experience managing teams of high-performing PD scientists/engineers

Competencies:

Adaptability: Responds resourcefully, flexibly, and positively when faced with new challenges, transitions, and demands. Willingly and effectively deals with the stress and complexities of various situations. Moves forward productively and optimistically under conditions of change and uncertainty.

Collaboration: Embodies and promotes collaboration and works effectively with others across the organization to achieve goals. Demonstrates proficient cross-company communication, cultural sensitivity, and partnership in interactions with others.  Involves others in decisions and plans and credits them for their contributions and accomplishments.

Communication: Creates an environment which promotes the free flow of communication and information throughout the organization. Communicates effectively in large and small groups. Openly shares knowledge and expertise. Listens actively and encourages the open expression of ideas and opinions.

Execution: Drives execution of strategic and operating plans while maintaining operational effectiveness. Conveys a strong sense of urgency around continuous improvement, achieving high quality results, and accelerating business performance. Addresses problems directly and drives changes necessary to achieve business objectives.

Relationship Building: Establishes and maintains strong relationships internally and externally. Respects and relates well to management, colleagues, peers, and direct reports. Champions a culture of respect, diversity and inclusion that values and respects individuals. Earns the respect of others through principled leadership, sound business ethics, and authenticity.

Location: Sudbury, MA

When You Join Allena You Will Have:

  • Free parking, Newton location reachable by public transportation (Green Line)
  • Customized and competitive health coverage including medical offered through BCBS (HMO/PPO), dental, and vision
  • Flexible Spending Accounts for medical and dependent care expenses
  • Eligible from the first day for 401K with 100% match of the first 4%
  • Robust package of Allena paid insurance coverage, including life insurance, short-term and long-term disability
  • 15 days of vacation and 5 personal days per year, in addition to 13 company holidays and 2 floating holidays
  • Winter Break: Allena is closed for a Winter Break between Christmas and New Year

TO ALL AGENCIES: Please, no phone calls or emails to any employee of Allena about our openings. All resumes submitted by search firms/employment agencies to any employee at Allena via email, the internet or in any form and/or method will be deemed the sole property of Allena, unless such search firms/employment agencies were engaged by Allena for this position and a valid agreement with Allena is in place. In the event a candidate who was submitted outside of the Allena agency engagement process is hired, no fee or payment of any kind will be paid.

Allena Pharmaceuticals is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law.

Senior Director, Clinical Research/Clinical Development

Description

This role reports to and collaborates closely with the Chief Medical Officer. Responsible for leading the global Phase III program for the lead compound in close partnership with Clinical Operations. The Senior Director will engage and establish relationships with the medical and patient communities to inform and execute the Phase III Program while ensuring strategic alignment of internal and external activities.

With other relevant Allena functions will also contribute to developing the strategy for the development of follow-on compounds. This teammate works collaboratively with other Allena functions, including Medical Affairs, Commercial, and Regulatory Affairs.

Who are we looking for?

  • An innovative person who will help Allena’s Clinical/Medical & Regulatory Affairs/Commercial teams in the execution of their goals.
  • MD is required; significant experience in nephrology, urology, rheumatology or endocrinology  preferred
  • Ideally, a minimum of 5 years of pharmaceutical clinical research or other highly relevant clinical research experience (e.g., academic research)

What are we looking for?

  • Leading the way:  A creative and learning-agile clinical leader, willing to challenge the status quo
  • Ownership:  A partner to jointly own our company’s goals, execution, and success
  • Working together:  A colleague to thrive on collaboration with our teammates
  • Loving what you do:  A team member with positive energy that is passionate about our mission

What are we offering?

  • Strategic leadership role for overall clinical development for Allena’s ALLN-177 Program
  • Membership within a growing, CARING and collegial organization
  • Exposure to pioneering science of the therapies that utilize the GI tract to degrade metabolites
  • Unique opportunity to help develop the platform and strategy of an expanding company

When You Join Allena You Will Have:

  • Free parking, Newton location reachable by public transportation (Green Line)
  • Customized and competitive health coverage including medical offered through BCBS (HMO/PPO), dental, and vision
  • Flexible Spending Accounts for medical and dependent care expenses
  • Eligible from the first day for 401K with 100% match of the first 4%
  • A robust package of Allena paid insurance coverage, including life insurance, short-term and long-term disability
  • PFMLA fully paid by Allena
  • 15 days of vacation and five personal days per year, in addition to 13 company holidays and two floating holidays
  • Winter Break: Allena is closed for a Winter Break between Christmas and New Year

Responsibilities:  

  • Serve as primary Medical / Scientific leader for the ALLN-177 Program. In that capacity:
    • Develop and implement medical/scientific strategy through strong engagement and learning from medical/KOL and patient communities
    • Participate in site identification and PI engagement, Investigator’s meetings, working closely with clinical operations personnel, CRO, etc.
    • Contribute to the development of Phase III study-related documents and statistical analysis plans
    • Partner closely with Clinical Operations to proactively identify program risks and create and implement mitigation strategies
    • Oversee and participate in ongoing safety monitoring, DSMB activities and the interpretation/analysis of trial results, including laboratory and biomarker data.
  • Oversee and contribute medical/scientific input to the preparation of clinical study reports, Investigational Brochures, statistical analysis plans and ISE, periodic safety update reports, briefing documents, annual reports, IND, BLA and other regulatory including the ISS documents

Skills/Abilities:

  • Proven success working with and effectively supporting cross-functional teams. 
  • We are looking for a leader who embraces and models positive and super collaborative style of work. Please see our leadership competencies below. 

Education and Experience:

  • MD is required; significant experience in nephrology, urology, rheumatology or endocrinology  preferred
  • Minimum 5 years of pharmaceutical clinical research or other highly relevant clinical research experience (e.g., academic research)
  • Knowledge of scientific principles of controlled clinical studies and working knowledge of GCP and FDA/ICH guidelines
  • Demonstrated experience in clinical research and ability to meaningfully contribute to development strategy, critical review of data, generation of research hypotheses, publication, and presentation of scientific information

Ability to travel up to 20-25% of the time

Location: Newton, MA

Competencies:

Adaptability: Responds resourcefully, flexibly, and positively when faced with new challenges, transitions and demands. Actively & positively seeks to find solutions to challenging problems without losing sight of the ultimate objective or vision. Moves forward productively and optimistically under conditions of change and uncertainty. 

Collaboration: Fosters and uses collaborative relationships among team members and between teams to facilitate the accomplishment of work goals. Involves others in discussions, decision making and planning, and credits them for their contributions and accomplishments. Regularly communicates with others on the team and within the organization with the goal of fostering enthusiasm, mutual trust, candor and respect.

Communication: Creates an environment that promotes the free flow of communication and information throughout the organization. Communicates effectively in large and small groups. Openly shares knowledge and expertise. Listens actively and encourages the open expression of ideas and opinions.

Execution: Drives towards high-quality results, continually monitoring progress against objectives. Understands and promotes assignment of authority and accountability and alignment of efforts across teams and functions. Addresses problems or misunderstandings and drives changes necessary to achieve business objectives. Conveys a strong sense of urgency around continuous improvement and follow-through for improving business performance. 

Relationship Building: Establishes and maintains strong relationships internally and externally. Respects and relates well to management, colleagues, peers, and direct reports. Champions a culture of respect, diversity and inclusion that values and respects individuals. Earns the respect of others through principled leadership, sound business ethics, and authenticity.

People Development: Creates comprehensive and robust talent plans, talent pools, and bench strength within the organization. Ensures that talent receives feedback, mentoring, training and development opportunities. Shapes roles and assignments in ways that leverage and develop individual’s capabilities. ​

Innovation: Generates and champions new ideas, approaches, and initiatives and creates an environment that nurtures and supports innovation. Encourages and accepts new ways of looking at problems and welcomes novel solutions. Leverages knowledge and best practices, fresh perspectives, breakthrough ideas, and new paradigms to improve processes and create value. 

Allena Pharmaceuticals is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law.

TO ALL AGENCIES: Please, no phone calls or emails to any employee of Allena about our openings. All resumes submitted by search firms/employment agencies to any employee at Allena via email, the internet or in any form and/or method will be deemed the sole property of Allena, unless such search firms/employment agencies were engaged by Allena for this position and a valid agreement with Allena is in place. In the event a candidate who was submitted outside of the Allena agency engagement process is hired, no fee or payment of any kind will be paid.

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